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487 Neutrophil extracellular traps (NETs), which are implicated in SLE pathogenesis, contain lower levels of polyubiquitinated proteins in SLE patients

The safety has not been well studied

We observe that the distinct Na + and carnitine cavities are bridged by a dual glutamine motif, previously implicated in Na + activation kinetics 46

Necroptosis The traditional view suggests that necrosis is a nonprogrammed or accidental cell death

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In contrast, SP treatment resulted in a dose-dependent down-regulation of these pro-inflammatory cytokines, demonstrating the anti-inflammatory effect of SP (Fig