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Male SpragueDawley rats weighing 250300 g were housed in wire-bottom cages in a constant temperature room of 22 (sd 2)C with 12-h light and dark cycles and fed standard rat chow

This transient bonding may induce a conformational change in the receptor, potentially triggering intracellular signaling pathways, predominantly those associated with G-proteins

If glycemia is suboptimal on treatment regimens that include basal insulin with other agents, bolus insulin at mealtimes (shortor rapid-acting analogues) may be added

Hoogendoorn R: Notochordal cells in mature caprine intervertebral discs