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This explains why high levels of oxidative stress is implicated not just in neurodegenerative conditions but cardiovascular diseases as well

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Human GLP-1 drugs have produced average weight reductions of 15 to 25 percent, though nausea, vomiting, diarrhea and weight regain after stopping treatment remain known concerns

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Lang Lehrskov L, Lyngbaek MP, Soederlund L et al (2018) Interleukin-6 delays gastric emptying in humans with direct effects on glycemic control