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Yes, for most people, 500 mg2 g/day is safe long term

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In yeast, Grx3/4 and Fra2, the cytosolic BolA ortholog, have been found together in a complex with Aft1, the major iron-dependent transcription factor ( in vitro studies have demonstrated that Grx3Fra2 complexes can donate a [2Fe-2S] cluster to Aft2, and genetic studies in yeast support this evidence of a direct FeS transfer to Aft1, studies have not yet made clear whether Grx3-type homodimers directly deliver FeS clusters or iron ions to targets in yeast or human cells

To this end, plant products have attracted several researchers across the world because of their selective toxicity against malignant cells [59,60,61]