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In addition, O 2 reacts with nitric oxide (NO) to generate peroxynitrite (ONOO) (Figure 2), which targets DNA, proteins, and lipids, causing DNA damage, dysfunction of enzymes, receptors, transporters, and membrane channels, as well as protein aggregation, mitochondrial dysfunction, and lipid peroxidation [15]

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Athletes face even higher rates, with soccer players experiencing hip and groin issues in up to 55 percent of men and 45 percent of women according to sports medicine research

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