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It is made from two amino acidslysine and methionineand is stored mainly in muscles, the heart, and the brain

it is the clinical basis for what follows

One common side effect of statins is muscle pain, and some research correlates statin use and a deficiency in CoQ10.6 A targeted study from 2025 revealed that a daily 200mg dose of CoQ10 could significantly reduce statin-related muscle pain.28 Additional research showed 100mg of CoQ10 supplementation could reduce symptoms of mitochondrial dysfunction brought on by statin use.7 Oxidative stress A systematic review and meta-analysis of papers looking at oxidative stress in athletes found that doses less than or equal to 300mg per day successfully reduced markers of oxidative stress after bouts of exercise

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