With regards to cellular senescence, Yang et al
If NHS access isnt available, private prescribers can also assess eligibility, including providers experienced in post-bariatric weight regain
On top of this, tretinoin promotes collagen and elastin production, which improves skin thickness and elasticity and makes hyperpigmentation look less pronounced
Gastrointestinal side effects occur in approximately 20 to 30% of patients at maximum dose, with nausea being most common during the first 2 to 4 weeks after each dose increase
Lifestyle modifications should be the first-line approach and include: Eating smaller, more frequent meals rather than large portions that overwhelm the already-slowed digestive system Avoiding eating within 2-3 hours of bedtime to allow adequate time for gastric emptying before lying down Elevating the head of the bed by 6-8 inches using blocks or a wedge pillow to reduce nocturnal reflux Identifying and avoiding trigger foods such as caffeine, alcohol, chocolate, spicy foods, citrus, and high-fat meals Maintaining an upright posture for at least 2-3 hours after meals Wearing loose-fitting clothing that doesn't compress the abdomen Pharmacological management may be appropriate for patients with persistent symptoms despite lifestyle modifications
Next week we will dive into the CJC peptide so stay tuned