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Zepbound , containing the active ingredient tirzepatide , is a newer medication that acts on both the GLP-1 and glucose-dependent insulinotropic polypeptide (GIP) receptors

It does this through independent mechanisms that happen to overlap with what the medication is already doing, which is why the combination often feels disproportionate rather than simply additive

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For many patients, that early success provides a huge psychological boost and keeps motivation high

For many people it has a strong biological and genetic basis, rooted in ancestors who survived famine by being extraordinarily good at storing calories

Cell Chem