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Their safety in pregnancy has not been fully established

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Of note, GLP-1 secretion in the blood increased with -glucan and showed an increasing trend with arabinoxylan, suggesting barley -glucan and arabinoxylan are fermented in the intestinal tract to favor endogenous GLP-1 release [30], thus mimicking SG effects

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While human risk remains unclear, patients with personal or family history of certain thyroid cancers should avoid these medications

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