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267 Delivery systems LNPs LNPs are self-assembled nanostructures with diameters of approximately 100 nm, capable of combining with negatively charged nucleic acids through electrostatic interactions

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This has been shown with alkali sulfides as early as 1898, pyruvic acid (1923), cysteine (1926), glutathione (1926), thioglycolic acid (1926) and many other thioacids (1928) 18

Sirtuins are proteins involved in DNA repair, gene regulation, and cellular stress responses

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