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doi: 10.1016/S0140-6736(20)30925-9 391

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Tirzepatide helps people with type 2 diabetes by: Improving insulin response : This means the body becomes better at using the insulin it produces, lowering blood sugar levels more effectively

When restarting after an extended break, beginning again at a lower dose is generally recommended to reduce the risk of gastrointestinal adverse effects, even if you previously tolerated higher doses well

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