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FSTL-1 has an adverse effect on disc homeostasis, accompanied by increased concentrations in the serum of IVDD patients, discs of rats with IVDD, and the cerebrospinal fluid of dogs with IVDD (125, 141)

SARM1 activation triggers axon degeneration locally via NAD + destruction

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The dose may be adjusted upward based on lab results and symptom response

Tacon AGJ, Shumway SE (2024) Critical need to increase aquatic food production and food supply from aquaculture and capture fisheries: trends and outlook