More importantly, compared with non-GLP-1RA/DPP-4i-treated plaques, GLP-1RA/DPP-4i-treated plaques presented greater SIRT6 expression and collagen content, with less inflammation and oxidative stress, indicating a more stable plaque phenotype and suggesting that GLP-1RAs can reduce plaque vulnerability [58]
Nausea, vomiting, and diarrhoeareported in clinical trials and listed in the SmPCcan lead to fluid loss and subsequent dehydration
Kalohexis is working on peptide therapies, including one for obesity that could offer an alternative approach to the GLP-1s that currently dominate the weight loss space
Arwert LI, Deijen JB, Drent ML
Therefore, larger and longer durations of randomized controlled trials, along with well-designed mechanistic studies, are needed to comprehensively unlock the exact roles and mechanisms of novel antidiabetic drugs in diabetic HFpEF in the future
HSA expenses are reported when you file taxes, and FSA expenses can still be audited
