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Extensive dermal melanocytosis that affects the ventral as well as dorsal trunk, persists, and progresses in extent over time can represent a sign of a lysosomal storage disease (eg, Hurler syndrome or GM1 gangliosidosis)

Any protocol above 1000mg daily should be approached as a therapeutic intervention rather than routine supplementation, with clear objectives and professional oversight

Conclusions Combination therapy was superior to monotherapies

In many instances, it takes a long time to confirm their existence

[2] It also generates reactive oxygen species under light exposure, which has been exploited in photodynamic therapy approaches for viral or bacterial inactivation