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These insights may help providers understand why a patient plateaued on one agent or whether a dual-agonist strategy might provide additional benefit

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Two things can shift your thyroid needs during weight loss: Absorption variability (especially early on with dose increases) BNF Body weight changes (thyroid replacement dose requirements can change as weight changes) A practical approach many clinicians use is: Check TSH ( free T4) about 68 weeks after : starting tirzepatide, or a significant dose escalation, or a big, sustained drop in weight NICE also flags that because tirzepatide delays gastric emptying, some oral medicines (particularly those with a narrow therapeutic index) may need monitoring during escalation

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I-TEAM has learned the FDA sent 30 warning letters to telehealth companies for illegally marketing compounded GLP-1s