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Errors at any stage can reduce potency and delay onset

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There is no difference for the primary outcome, FPG in one group (MD 3.40, 95% CI [7.600.80]

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In age-related neurological disorders such as AD, the catalytic activity of pyruvate dehydrogenase is suppressed, leading to decreased acetyl-CoA production and impaired TCA cycle energy metabolism (Sang et al