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Nature neuroscience 2019;22, 1806-1819, doi:10.1038/s41593-019-0505-1

4 The 2020 American College of Rheumatology guidelines 5 conditionally recommend screening for the human leukocyte antigen (HLA)-B*58:01 allele in certain populations before starting allopurinol, as carriers of this allele have a higher risk of TEN than noncarriers

Identification of female-enriched and disease-associated microglia (FDAMic) contributes to sexual dimorphism in late-onset Alzheimer's disease

Understanding anhedonia: a qualitative study exploring loss of interest and pleasure in adolescent depression

In the brain, TNF- acts synergistically with IFN- to sustain microglial and astrocytic activation [182], promoting the induction of pro-oxidant enzymes, such as iNOS and NADPH oxidase, that contribute to oxidative stress and dopaminergic neurodegeneration [189]

Consult your doctor for appropriate monitoring advice