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RC: These medications are not just about the number on the scale

GLP-1 therapy can improve: Type 2 diabetes Blood pressure Fatty liver disease Sleep apnea PCOS Cholesterol Joint pain Mobility Quality of life Many patients also report increased energy and confidence as they lose weight

We thank Joanna Loizou and Anna Schrempf for providing p53 mutant human TERT-immortalized retinal pigment epithelial 1 (RPE1) cells

The gut houses about 80% of the immune system

when we talk about GLP-1 in this context, we usually mean the direct receptor agonist drugs such as those listed above

Ozempic, Wegovy and Mounjaro are all administered on a weekly basis through a subcutaneous injection, with the outlier being Mounjaro due to the significantly higher starting dosage (2.5mg compared to 0.5mg for the other two)