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[15] In both trials, after 72 weeks of treatment, participants who received tirzepatide at all three dose levels experienced a statistically significant reduction in body weight compared to those who received placebo, and greater proportions of participants who received tirzepatide achieved at least 5% weight reduction compared to placebo

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However, the data suggests that tirzepatide tends to enable a higher percentage of individuals to reach greater weight loss milestones (e.g., 15%, 20%, 25%) compared to semaglutide