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Dermatology research here is genuinely mixed some studies show topical and oral glutathione reducing UV-related damage and improving tone evenness, but a 2025 systematic review in a peer-reviewed dermatology journal was direct about it: evidence for dramatic skin-lightening is limited, and the ethics of marketing it that way are actively debated among dermatologists

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Main body We systematically reviewed cases reported in the literature on hyperammonemia in adulthood

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Peroxynitrite: a key molecule in skin tissue response to different types of stress