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Es esperable, en este tipo de diseo, que las comorbilidades asociadas pueden variar y puedan explicar la mayor mortalidad detectada en el grupo de ciruga

After spending $120 million on weight-loss drugs in fiscal 2025, the Group Insurance Commission, which provides health insurance to all state employees and retirees, decided it would offer the drugs a new way in 2026

The other three DPP-4 inhibitors, teneligliptin, anagliptin and trelagliptin, are only approved in the Japanese and Korean markets

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The high prevalence of gastrointestinal adverse effects with any of these agents must be weighed against the benefits of weight loss and the associated improvement in cardiometabolic comorbidities