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Thus, NTHi may take advantage of the same import systems to both obtain haem and confer resistance to the innate mucosal immune response and oxidative stress (Mason et al., 2006

doi: 10.1007/s00125-015-3660-2 16 WolvertonDBlairMM

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Cellular senescence Evolutionary considerations suggest aging is caused not by active gene programming but by evolved limitations in somatic maintenance, resulting in a build-up of damage. (Kirkwood, 2005) In this section, we will discuss important notions in cellular senescence and highlight selected recent findings, related to glial heterogeneity and disease association

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