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64 GaleaE.RegunathanS.EliopoulosV.FeinsteinD

doi:10.1124/jpet.114.218735 PubMed: 25187433 Wright JW, Harding JW

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+ Common signs of low B12 include persistent tiredness or low energy, brain fog or poor concentration, pins and needles or numbness in the hands and feet, a sore or red tongue, mouth ulcers, low mood, and looking pale

Presumably, Epitalons effect on AANAT and pCREB underlies the peptide regulation of pineal cell activity