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Blood 79:32333238 Craig ME, Kim KW, Isaacs SR, Penno MA, Hamilton-Williams EE, Couper JJ, Rawlinson WD (2019) Early-life factors contributing to type 1 diabetes

Syringe needle bending when puncturing the stopper Rubber vial stoppers can be tough to puncture with thin insulin needles

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Tang N, Yuan S, Luo Y, Wang A-J, Sun K, Liu N-N, Tao K

481 However, the hydrophilic structure of deferoxamine results in poor absorption and rapid metabolism which forces frequent parenteral administration in patients (over 8 to 12 h per day), thus imposing a significant treatment burden

Ce phnomne serait li la formation de sulfites au contact des muqueuses bronchiques