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Semaglutide works by slowing gastric emptying, reducing hunger signals, and improving insulin sensitivity, all contributing to sustainable weight loss when combined with lifestyle changes

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Ask patients to review key behaviours (including what they eat, when they eat, how they exercise) during their weight management journey

Medication timing is important to optimize absorption of both medications

It works by: Increasing insulin secretion when blood sugar levels are high Slowing gastric emptying Suppressing appetite and promoting satiety These actions make semaglutide effective not only for controlling blood glucose but also for aiding in substantial weight loss

Prednisolone is a glucocorticoid, which acts as an immunosuppressant to reduce the destruction of platelets by the immune system (NHLBI 2012)