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Consquence : pas de conjugaison possible du glutathion, et donc un organisme qui aura des difficults traiter correctement les xnobiotiques qui nous entourent (mdicaments, pesticides, additifs alimentaires, etc.)

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Artesunate activates the ATF4-CHOP-CHAC1 pathway and affects ferroptosis in Burkitts lymphoma

eLife 8 , e44452 (2019)

This would essentially result in the tamoxifen you took as being labelled ineffective as the body would not be able to process it 1

Differential distribution of gene polymorphisms associated with hypercholesterolemia, hypertriglyceridemia, and hypoalphalipoproteinemia among Native American and Mestizo Mexicans