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Additionally, Ile-52 and Glu-64 were generally maintained as either hydrophobic or polar residues across GST classes [82]

A high GSH concentration and a reduced cellular state are known to promote self-renewal, allowing the GSH-to-ROS ratio to be a key determinant of cell fate ( In human embryonic stem cells, CHAC2 is highly enriched and is crucial for maintaining self-renewal capacity

& Bushweller, J

exerts a protective effect on benzalkonium chloride-induced mouse dry eye model

Ferreira et al, 2001