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The copper component serves as an essential cofactor for lysyl oxidase and lysyl hydroxylase, enzymes critical for proper collagen cross-linking

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The human research is early but the preclinical literature is deep and consistent

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A 2025 IRB-approved pilot study published in PubMed reported no adverse effects following intravenous administration of 20mg in 2 healthy adults, with monitored biomarkers (heart, liver, kidneys, thyroid, and blood glucose) returning normal results