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However, additional studies are warranted to validate these findings (Varnum et al., 2023)

These effects are mediated by the suppression of IkB phosphorylation that is necessary for the release of NF-kB from the inhibitor and its further transportation in the nucleus (Gao et al., 2022)

The new data suggests the problem may be dose-dependent, meaning higher exposure to semaglutide could significantly increase the risk of optic nerve injury

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