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A high rate of comorbid immune disorders is also evident, such as Hashimoto thyroiditis and rheumatoid arthritis, and common variable immunodeficiency has been reported in patients with dysautonomia

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The most common presentations of thyroid dysfunction include nonspecific complaints such as tiredness, weight change without obvious cause, mood alteration, and gastrointestinal disorders

Some patients experience mild nausea as their body adjusts, which typically resolves within 1-2 weeks

Clinical trials of once-weekly 2.4 mg semaglutide have shown significant, sustained weight loss when combined with lifestyle intervention