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In some regions, individuals can buy it over the counter or online without a prescription

Yes, split dosing is a valid approach, particularly for doses at the higher end of the range (450-500mcg daily)

Taking into account (i) the anti-autoimmunity and anti-cancer properties of the omega-3 PUFA, (ii) the increasing incidence of both autoimmune thyroiditis and thyroid cancer worldwide, (iii) the predisposing role for thyroid cancer exerted by autoimmune thyroiditis, and (iv) the risk for developing metabolic and cardiovascular disorders conferred by both elevated/trendwise elevated serum TSH levels and thyroid autoimmunity, then there is enough rationale for the omega-3 PUFA as measures to contrast the appearance and/or duration of Hashimotos thyroiditis as well as to correct the slightly elevated serum TSH levels of subclinical hypothyroidism

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