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Pancreatic Lipase Inhibition: Limits the creation of new fat cells

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IgE, immunoglobulin E

Avg weight loss (72 weeks): ~20.9% (SURMOUNT-1) Side Effects by Dose Level Side effects are dose-dependent and most common during the first 12 weeks after each escalation

But the mechanisms that were helping you eat less and feel satisfied sooner gradually return to their pre-treatment baseline