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Pretreatment with losartan (3 mg/kg) significantly decreases MDA levels and reverses the negative effects of LPS on the activity of CAT and SOD in the hippocampal and cortical tissues (116)

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The mechanism of action of tamoxifen cytotoxicity when used at concentrations above the nanomolar range has been linked to the induction of oxidative stress, through the engagement of ER -unrelated, undefined mediators that activate oxidative enzymes or modulate Ca 2+ homeostasis, increasing the intracellular levels of reactive oxygen species (ROS) or oxidized molecules ( The Antimicrobial Activity of Tamoxifen Tamoxifen is effective against a broad range of life-threatening infections

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Are mitophagy enhancers therapeutic targets for Alzheimers disease

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