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25 Conclusions Understanding the enteroinsular axis has been the basis of seminal advancements in the therapeutic approach to diabetes management, with translation of research discoveries into effective pharmacologic therapies

Not all obese individuals develop OA, and not all OA patients are obese

Lean proteins: Eggs, chicken, and seafood

No significant pharmacokinetic interaction observed between cagrilintide and semaglutide 1-3

Therefore, Erastin not only directly induces necroptosis but also amplifies its occurrence through the ROS generated during ferroptosis, establishing a synergistic interaction between ferroptosis and necroptosis