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Vitamin E increases production of vasodilator prostanoids in human aortic endothelial cells through opposing effects on cyclooxygenase-2 and phospholipase A2
Mechanistically, it can dampen the pro-inflammatory response by decreasing the transcription of pro-inflammatory cytokines through direct DNA binding to Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-B) (Wang and He, 2022)
People with depression may have lower ghrelin levels and experience cognitive decline
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