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Pharmacokinetics and effects on cyst(e)ine in plasma and urine

The reason supervised therapy exists is that signaling molecules belong in a clinical workflow, with a licensed prescriber, a regulated pharmacy, a documented evaluation, and a follow up plan

Several enzymes involved in ATP production contain Fe-S clusters in the active site and are subject to similar inactivation by superoxide, including oxoglutarate dehydrogenase of the tricarboxylic acid cycle, as well as ETC complexes IIII

LI and GB: provided support for the experiment, designed and elaborated the study, and supervised the writing of the manuscript

Winterbourn et al., 2002)