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The warning on semaglutide about increased suicidal ideation risk was investigated by the FDA in 2024 and the agency found no causal signal, but psychiatric populations are more sensitive to this kind of scrutiny

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Diabetes Obes Metab 23(9):21772182 Aroda VR, Rosenstock J, Terauchi Y, Altuntas Y, Lalic NM, Morales Villegas EC, Jeppesen OK, Christiansen E, Hertz CL, Haluzk M (2019) PIONEER 1: randomized clinical trial of the efficacy and safety of oral semaglutide monotherapy in comparison with placebo in patients with type 2 diabetes