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Keywords: cardiovascular disease, chronic kidney disease, end-stage renal disease, hyperhomocysteinemia, folic acid, vitamin B12 1

Good candidates generally have stable health status, understand the experimental nature of the therapy, and commit to appropriate monitoring protocols

Blood tests can look for anaemia, folate deficiency and the size of red blood cells

Phosphorylation of the DSGIS motif in NRF2 mediated by glycogen synthase kinase-3 beta (GSK-3) promotes the binding of -TrCP to NRF2 which is therefore marked for ubiquitination and then degraded by the proteasome [145, 149,150,151]

This heat map demonstrated significant differences between the samples (Fig

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