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Haem-iron acquisition in NTHi is regulated in accordance with environmental iron-bioavailability by iron-repressive transcriptional regulators such as fur , with the result that iron uptake is coordinated with storage and efflux to ensure iron homeostasis (Harrison et al., 2013)

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Furthermore, pulmonary endogenous stem cell activation can encourage tissue healing and lessen the need for ferroptosis-induced cell replacement

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