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FIGURE 2 Collectively, the evidence reviewed in this section supports the conclusion that appetite and behavioral peptide systems have been constrained more by conceptual caution than by biological inadequacy

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But if you want to mention a little bit about what you've done in the past, I think that will be helpful because what I always like to know is, you know, where did the idea come from

This dual action, promoting the breakdown of existing fat while simultaneously slowing the creation of new fat, makes the theoretical mechanism appealing

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In particular, NRF2 strongly activates cystine uptake coupled with glutamate excretion and glutathione synthesis, which increases consumption of intracellular glutamate