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Because mitochondria lack catalase, the metabolism of hydrogen peroxide is accomplished mainly by GSH, with the participation of either GSH peroxidase or peroxiredoxin, and by the later conversion of GSSG back into GSH by the NADPH-dependent GSSG reductase (GR)

2022;18:e1010159

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Glutathione and its anti-aging and antimelanogenic effects

This lessens cell damage and slows down aging

High dose oral supplementation is an effective alternative to parenteral treatment Randomized studies of daily high oral doses of 1,0002,000 g have shown equivalence or superiority to injected B 12