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call 999 immediately for breathing difficulty, throat swelling, or collapse

The substitution wouldn't address the same research question

The key requirement is a valid prescription from a licensed physician for a diagnosed medical condition

Nature 607 , 169175 (2022)

Some contraindications (reasons not to take B12 shots) include: Allergies to cyanocobalamin or methylcobalamin Kidney or liver disease Eye issues, especially if you have Lebers disease A current infection If youre taking medication related to bone marrow You should talk to your doctor about the above conditions before getting B12 injections

A.AndringaA.et al (1999)