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doi: 10.1056/NEJMoa1107494 [PubMed] 24453083 Thakur KT, Probasco JC, Hocker SE, Roehl K, Henry B, Kossoff EH, Kaplan PW, Geocadin RG, Hartman AL, Venkatesan A, Cervenka MC

Additionally, practitioners may be hesitant to recommend GHK-Cu formulations without long-term clinical data, slowing adoption in professional settings and limiting market penetration

Consequently, intravenous (IV) administration is preferred in children because of the higher bioavailability and reduced PK variability compared to oral formulations (Palmer et al., 2016)

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doi: 10.1111/j.1600-065X.2008.00628.x 31 ManhartNVierlingerKSpittlerABergmeisterHSautnerTRothE