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Understanding why diagnosis takes so long requires examining the complex interplay between patient factors, provider knowledge, healthcare system structures, and the inherent challenges of the condition itself

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Extensive studies of these pathways have uncovered upstream regulators (e.g., Legumain, ALR, and Panx1), deepening the mechanistic understanding of renal I/R ferroptosis and expanding therapeutic opportunities for targeting ferroptosis in I/R AKI

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Inhibition of the Development of Collagen-Induced Arthritis in Rhesus Monkeys by a Small Molecular Weight Antagonist of CCR5