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The EXAMINE and SAVOR-TIMI 53 studies were excluded from sensitivity analyses because DPP-IV inhibitor drugs did not show CV benefit in their individual trials

Samples were collected in EDTA-coated tubes, which were further coated with 0.1 mmol/l Ile-Pro-Ile (Sigma Aldrich)

Neurotox Res 39(5):13931404 Chen N, Wang XC, Fan LL, Zhu YH, Wang Q, Chen YB (2022) Berberine ameliorates lipopolysaccharide-induced cognitive impairment through SIRT1/NRF2/NF-B signaling pathway in C57BL/6J Mice

Ideally, wrote Davis in a follow-up email, the government agency will spell out its specific concerns about each peptide, and then describe what data would be needed for the FDA to overturn its prohibitions

"I'm hoping the drug makers have to change this drug," she said