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Indeed, filing in territories such as the US means that protection of, e.g., methods of treatment, can be obtained, which are excluded from patentability in territories including Europe and Japan

[11] [12] Other key factors include: Dose level : Higher doses (e.g., 12 mg in trial protocols) produced greater weight loss than lower doses, though they were also associated with a higher incidence of gastrointestinal side effects

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