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Less muscle means a slower resting metabolic rate, which makes keeping weight off harder over time

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If you are sleeping fewer than seven hours per night or experiencing significant chronic stress, these factors may be blunting the medication response

GLP-1 receptors are found in several brain regions, including: The ventral tegmental area (VTA) The nucleus accumbens The prefrontal cortex When activated by GLP-1, these receptors appear to reduce the release of dopamine in response to addictive substances

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