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We advocate for further research into their application in AS and recommend the inclusion of AS patients in future clinical trials to better understand their impact on disease progression and patient outcomes

Cash JG, Kuhel DG, Basford JE, Jaeschke A, Chatterjee TK, Weintraub NL, Hui DY

Early research suggests these medications may ease depressive symptoms by dampening inflammation and influencing brain signaling, though clinical data remain limited