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Diabetics on Medication: Because inositol lowers blood sugar, taking it alongside insulin or drugs like Metformin or Glyburide could theoretically cause hypoglycemia (blood sugar dropping too low)

It works by modulating the nitric oxide pathway, promoting angiogenesis, and accelerating tendon-to-bone healing through upregulation of growth factor expression

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Two large, randomized control trials investigating liraglutide and semaglutide have suggested worsening retinopathy as an adverse effect of GLP-1RA use