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Beneficial effects of IGF-I treatment in ALS have been demonstrated both in vivo and in vitro , from which IGF-I has been postulated as an important factor for the maintenance and survival of motor neurons in the spinal cord by activating clue pathways as PI3K/Akt and p44/42 MAPK[333] and ameliorating the superoxide effect[334]

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Common side effects of Byetta include nausea, indigestion, vomiting, diarrhea, and/or constipation

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Die gleichzeitige Hochregulation von TIMP-1 und TIMP-2, den natuerlichen Inhibitoren der MMPs, deutet auf einen regulierenden Einfluss von GHK-Cu auf das Gleichgewicht zwischen Matrixaufbau und Matrixabbau hin Pickart et al., 2015